Short-term feed restriction induces inflammation and an antioxidant response via cystathionine-β-synthase and glutathione peroxidases in ruminal epithelium from Angus steers.

ABSTRACT: Decreased intake is induced by stressors such as parturition, transportation, dietary transitions, and disease. An important function of one-carbon metabolism (OCM) is to produce the antioxidant glutathione to help reduce oxidative stress. Although various components of OCM are expressed in the bovine rumen and small intestine, the relationship between reduced feed intake, OCM, and antioxidant mechanisms in gut tissues is unknown. This study aimed to assess alterations in immune and antioxidant pathways in ruminal epithelium due to acute feed restriction (FR). Seven group-housed ruminally cannulated Angus steers (663 ± 73 kg body weight, 2 yr old) had ad libitum access to a finishing diet (dry-rolled corn, corn silage, modified wet distiller's grains) during 15 d of a pre-FR period (PRE).

SUBMITTER: Jiang Q 

PROVIDER: S-EPMC11465371 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature