Insulin resistance and sarcopenia: a prognostic longitudinal link to stroke risk in middle-aged and elderly Chinese population.

ABSTRACT:

Background

Stroke is the leading cause of death in middle-aged and elderly people in China. Insulin resistance (IR) and sarcopenia are both closely associated with metabolic diseases. However, the relationship between these two indicators and stroke has not been fully investigated. The aim of this study was to investigate the relationship between IR and sarcopenia and the risk of new-onset stroke.

Methods

Using longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2018, Cox proportional hazards models were used to determine the association between IR surrogate indicators and sarcopenia status with stroke incidence.

Results

In the present study, during a median 7 years of follow-up, we included 7009 middle-aged and elderly resi

SUBMITTER: Guo C 

PROVIDER: S-EPMC11465621 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature