Cytotoxicity and Epithelial Barrier Toxicity of Fine Particles from Residential Biomass Pellet Burning.

ABSTRACT: Rising environmental concerns associated with the domestic use of solid biofuels have driven the search for clean energy alternatives. This study investigated the in vitro toxicological characteristics of PM_2.5 emissions from residential biomass pellet burning using the A549 epithelial cell line. The potential of modern pellet applications to reduce PM_2.5 emissions was evaluated by considering both mass reduction and toxicity modification. PM_2.5 emissions from raw and pelletized biomass combustion reduced cell viability, indicative of acute toxicity, and also protein expression associated with epithelial barrier integrity, implying further systemic toxicity, potentially via an oxidative stress mechanism. Toxicity varied between PM_2.5 emiss

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11465659 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature