Prognostic role of suPAR in acute pancreatitis: A protocol for systematic review.

ABSTRACT:

Background

Acute pancreatitis (AP) is a common emergency condition with high morbidity, mortality, and socio-economic impact. Soluble urokinase plasminogen activator receptor (suPAR) is a potential biomarker for AP prognosis. This study systematically reviews the literature on suPAR's prognostic roles in assessing AP severity, organ failure, mortality, and other pathological markers.

Methods

A comprehensive search of 5 databases up to March 19, 2023, was conducted, selecting cohort studies that examined suPAR's relationship with AP outcomes. Outcome variables included AP severity, organ failure, mortality, hospital stay length, and suPAR's association with other inflammatory markers. Our paper has been registered on Prospero (ID: CRD42023410628).

Results

Nine prospect

SUBMITTER: Rehan ST 

PROVIDER: S-EPMC11466201 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature