Does exogenous glucocorticoid administration during pregnancy precipitate the timing of labor? A scoping review.

ABSTRACT:

Introduction

To investigate whether synthetic (s) glucocorticoids (GCs) administered between the 24th and the 34th gestational weeks in pre-term labor might precipitate labor, studies on sGCs administration were reviewed. The physiology of endogenous glucocorticoid-related increase in fetal-maternal circulation and its association with labor, followed by a scoping review of studies on exogenous sGCs administered for fetal lung maturation and the timing of labor, were included.

Materials and methods

The methodology of systematic reviews was followed. MEDLINE, Cochrane Library, and Google Scholar databases were searched until October 2023, for original studies investigating the administration of sGCs in pregnancies risking pre-term labor. Duplicates were removed, and 1867 abst

SUBMITTER: Karampitsakos T 

PROVIDER: S-EPMC11466246 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature