Comparing the prognostic impact of 131I and/or artificial liver support system on liver function failure combined with hyperthyroidism.

ABSTRACT:

Objective

Hyperthyroidism, a prevalent endocrine disorder, can lead to complications such as liver failure due to the liver's essential role in thyroid hormone metabolism. The study aimed to elucidate the respective contributions of 131I and/or ALSS in managing hyperthyroidism alongside liver failure.

Methods

A retrospective analysis was carried out on 74 patients diagnosed with severe liver failure in the context of Graves' disease. Patients were categorized into three groups: group A (n = 34) received 131I treatment, group B (n = 17) underwent 131I and ALSS treatment, and group C (n = 24) received artificial liver support system (ALSS) treatment alone.

Results

Throughout the treatment period, the liver function indexes in all groups exhibited a declining trend. The

SUBMITTER: Fang D 

PROVIDER: S-EPMC11466263 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature