Risk of systemic lupus erythematosus flare after COVID-19 hospitalization: A matched cohort study.

ABSTRACT:

Objective

To analyze the risk of systemic lupus erythematosus (SLE) flare after admission for COVID-19.

Methods

We performed a matched cohort study using the Assistance Publique-Hôpitaux de Paris Clinical Data Warehouse which collects structured medical, biological and administrative information from 11 million patients in Paris area, France. Each SLE patient hospitalized with a COVID-19 diagnosis code between March 2020 and December 2021 was matched to one SLE control patient with an exact matching procedure using age ±3 years, gender, chronic kidney disease, end-stage renal disease, and serological activity. The main outcome was a lupus flare during the 6 months follow-up. A flare was considered if a) documented by the treating physician in the patient's EHR and b) justify

SUBMITTER: Mageau A 

PROVIDER: S-EPMC11466388 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature