Multisensory perceptual and causal inference is largely preserved in medicated post-acute individuals with schizophrenia.

ABSTRACT: Hallucinations and perceptual abnormalities in psychosis are thought to arise from imbalanced integration of prior information and sensory inputs. We combined psychophysics, Bayesian modeling, and electroencephalography (EEG) to investigate potential changes in perceptual and causal inference in response to audiovisual flash-beep sequences in medicated individuals with schizophrenia who exhibited limited psychotic symptoms. Seventeen participants with schizophrenia and 23 healthy controls reported either the number of flashes or the number of beeps of audiovisual sequences that varied in their audiovisual numeric disparity across trials. Both groups balanced sensory integration and segregation in line with Bayesian causal inference rather than resorting to simpler heuristics. Both also sho

SUBMITTER: Rohe T 

PROVIDER: S-EPMC11466413 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature