Selection determines therapeutic effects: a retrospective analysis of the application of different frailty tools in elderly patients with multiple myeloma.

ABSTRACT:

Objective

The aim was to explore the effectiveness of the International Myeloma Working Group Frailty Index (IMWG-FI), Mayo Score, UK Myeloma Research Alliance Risk Profile (MRP), and Intergroupe Francophone du Myélome (IFM) simplified frailty scale for classifying frailty in elderly multiple myeloma (MM) patients and compare the validity of different frailty tools.

Methods

Eighty-four newly diagnosed MM patients aged ≥ 60 years in HeBei University Hospital were evaluated by the IMWG-FI, Mayo score, MRP score and IFM scale, and consistency and survival analyses were performed using Cohen's kappa coefficients and the Kaplan‒Meier method, respectively.

Results

A total of 64 patients (76.2%) were identified as frail by at least one frailty tool; 14 (21.9%) were identifie

SUBMITTER: Li Y 

PROVIDER: S-EPMC11466923 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature