Soluble transferrin receptor is associated with red blood cell transfusion in infant cardiac surgery.

ABSTRACT:

Background

Iron deficiency (ID) is linked to an increased need for perioperative red blood cell (RBC) transfusion in cardiac surgery. Traditional markers used to assess ID are often influenced by inflammation, whereas soluble transferrin receptor (sTfR) is less affected by inflammation. Therefore, the purpose of this study is to explore the relationship between sTfR levels and the need for high-volume RBC transfusion in pediatric cardiac surgery patients.

Methods

From August 2021 to July 2022, 236 low-weight infants (≤10 kg) who underwent cardiac surgery were included in this study. Preoperative sTfR levels and the volume of RBCs perioperatively transfused were recorded. Receiver operating characteristic (ROC) curve analysis and multivariable logistic model were used to expl

SUBMITTER: Gao P 

PROVIDER: S-EPMC11467239 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature