Effect of immunosuppressive agents on clinical outcomes in idiopathic membranous nephropathy.

ABSTRACT:

Background

Few comparative studies on the effects of immunosuppressants in patients with idiopathic membranous nephropathy have been conducted.

Methods

Data from 489 patients who received conservative treatment or immunosuppressants were retrospectively analyzed by propensity score matching. Primary outcomes were complete or partial remission (CR or PR) of proteinuria, and secondary outcomes were renal survival and infection.

Results

Of the 489 patients, 357 (73.0%) received immunosuppressants. Propensity score matching identified 82 patients from the conservative group and 82 patients in the immunosuppressant group. CR or PR at 12 months was significantly higher in the immunosuppressant group compared with the conservative group for the total population (p = 0.002) a

SUBMITTER: Choi JY 

PROVIDER: S-EPMC11467357 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature