Skin-directed radiotherapy for primary cutaneous T-cell lymphomas.

ABSTRACT:

Purpose

To evaluate the efficacy and toxicities of skin-directed radiotherapy (RT) in primary cutaneous T-cell lymphoma (CTCL).

Materials and methods

We retrospectively analyzed 57 CTCL lesions treated with skin-directed RT between January 2000 and December 2022. Lesions were categorized into three distinct groups: early-stage disease treated with local RT, advanced-stage disease treated with local RT, and advanced-stage disease treated with total skin electron beam therapy (TSEBT). Treatment outcomes, including response rates, recurrence patterns, and local progression probability, were assessed for each group.

Results

Mycosis fungoides (MF) constituted 90.9% of the advanced-stage pathologies, while CD4+ primary cutaneous small/medium T-cell lymphoproliferative disor

SUBMITTER: Kim HU 

PROVIDER: S-EPMC11467483 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature