Association between the duration of smoking cessation and α-Klotho levels in the US middle-aged and elderly population.

ABSTRACT:

Background

α-Klotho is a molecule associated with aging and several diseases. Previous studies have reported decreased levels of serum α-Klotho (SαKl) in smokers compared to never smokers. Interestingly, we also found the SαKl level could partly recover in those who quit smoking. The objective of this study was to investigate SαKl levels in the US population who quit smoking for a certain period.

Methods

A total of 9268 participants, ranging in age from 40 to 79 years were enrolled in this cross-sectional study, 37.04 % were identified as former smoker. Data from the NHANES conducted between 2007 and 2016 were utilized for analysis. The association between the period of smoking cessation and SαKl levels was evaluated through multivariate linear regression models. Additionall

SUBMITTER: Du R 

PROVIDER: S-EPMC11467537 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature