Magnetic Chitosan Bionanocomposite Films as a Versatile Platform for Biomedical Hyperthermia.

ABSTRACT: Responsive magnetic nanomaterials offer significant advantages for innovative therapies, for instance, in cancer treatments that exploit on-demand delivery on alternating magnetic field (AMF) stimulus. In this work, biocompatible magnetic bionanocomposite films are fabricated from chitosan by film casting with incorporation of magnetite nanoparticles (MNPs) produced by facile one pot synthesis. The influence of synthesis conditions and MNP concentration on the films' heating efficiency and heat dissipation are evaluated through spatio-temporal mapping of the surface temperature changes by video-thermography. The cast films have a thickness below 100 µm, and upon exposure to AMF (663 kHz, 12.8 kA m^-1), induce exceptionally strong heating, reaching a maximum temperature increase o

SUBMITTER: Barra A 

PROVIDER: S-EPMC11468069 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature