Catalyzing Generation and Stabilization of Oxygen Vacancies on CeO_2-x Nanorods by Pt Nanoclusters as Nanozymes for Catalytic Therapy.

ABSTRACT: Although CeO₂ nanomaterials have been widely explored as nanozymes for catalytic therapy, they still suffer from relatively low activities. Herein, the catalyzing generation and stabilization of oxygen vacancies on CeO₂ nanorods by Pt nanoclusters via H₂ gas reduction under mild temperature (350 °C) to obtain Pt/CeO_{2- x} , which can serve as a highly efficient nanozyme for catalytic cancer therapy, is reported. The deposited Pt on CeO₂ by the atomic layer deposition technique not only can serve as the catalyst to generate oxygen vacancies under mild temperature reduction through the hydrogen spillover effect, but also can stabilize the generated oxygen vacancies. Meanwhile, the oxygen vacancies also provide anchoring sites fo

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11468536 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature