Best practice exercise for emerging depression in multiple sclerosis: A systematic review and meta-analysis.

ABSTRACT:

Objective

To examine the effects of instructor-led exercise on depression symptoms in adults with multiple sclerosis, with a focus on moderating factors to treatment response.

Data sources

Cochrane Library, Embase, PEDro, PsycINFO and PubMed databases were searched until 21 April 2024.

Review methods

The reporting quality of included studies assessed (PEDro and TESTEX scales). Hedges' g effect sizes were calculated and pooled using random and mixed-effects modelling.

Results

Twenty-two independent studies (k), representing 785 participants with relapsing remitting or progressive MS, were included. Individual studies varied in their reporting quality (PEDro range: 3-8) and did not routinely detail exercise parameters (TESTEX range: 5-13). Nonethele

SUBMITTER: Ahola K 

PROVIDER: S-EPMC11468659 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature