Collaborative augmented reconstruction of 3D neuron morphology in mouse and human brains.

ABSTRACT: Digital reconstruction of the intricate 3D morphology of individual neurons from microscopic images is a crucial challenge in both individual laboratories and large-scale projects focusing on cell types and brain anatomy. This task often fails in both conventional manual reconstruction and state-of-the-art artificial intelligence (AI)-based automatic reconstruction algorithms. It is also challenging to organize multiple neuroanatomists to generate and cross-validate biologically relevant and mutually agreed upon reconstructions in large-scale data production. Based on collaborative group intelligence augmented by AI, we developed a collaborative augmented reconstruction (CAR) platform for neuron reconstruction at scale. This platform allows for immersive interaction and efficient collabora

SUBMITTER: Zhang L 

PROVIDER: S-EPMC11468770 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature