X-Ray Nanothermometry of Nanoparticles in Tumor-Mimicking Tissues under Photothermia.

ABSTRACT: Temperature plays a critical role in regulating body mechanisms and indicating inflammatory processes. Local temperature increments above 42 °C are shown to kill cancer cells in tumorous tissue, leading to the development of nanoparticle-mediated thermo-therapeutic strategies for fighting oncological diseases. Remarkably, these therapeutic effects can occur without macroscopic temperature rise, suggesting localized nanoparticle heating, and minimizing side effects on healthy tissues. Nanothermometry has received considerable attention as a means of developing nanothermosensing approaches to monitor the temperature at the core of nanoparticle atoms inside cells. In this study, a label-free, direct, and universal nanoscale thermometry is proposed to monitor the thermal processes of nanoparti

SUBMITTER: Lopez-Mendez R 

PROVIDER: S-EPMC11469036 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature