Continuous Microfiber Wire Mandrel-Less Biofabrication for Soft Tissue Engineering Applications.

ABSTRACT: Suture materials are the most common bioimplants in surgical and clinical practice, playing a crucial role in wound healing and tendon and ligament repair. Despite the assortment available on the market, sutures are still affected by significant disadvantages, including failure in mimicking the mechanical properties of the tissue, excessive fibrosis, and inflammation. This study introduces a mandrel-less electrodeposition apparatus to fabricate continuous microfiber wires of indefinite length. The mandrel-less biofabrication produces wires, potentially used as medical fibers, with different microfiber bundles, that imitate the hierarchical organization of native tissues, and tailored mechanical properties. Microfiber wire morphology and mechanical properties are characterized by scanning e

SUBMITTER: Adamo A 

PROVIDER: S-EPMC11469050 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature