Impaired oxygenation after lung resection: Incidence and perioperative risk factors.

ABSTRACT:

Study objective

To estimate the incidence of postoperative oxygenation impairment after lung resection in the era of lung-protective management, and to identify perioperative factors associated with that impairment.

Design

Registry-based retrospective cohort study.

Setting

Two large academic hospitals in the United States.

Patients

3081 ASA I-IV patients undergoing lung resection.

Measurements

79 pre- and intraoperative variables, selected for inclusion based on a causal inference framework. The primary outcome of impaired oxygenation, an early marker of lung injury, was defined as at least one of the following within seven postoperative days: (1) SpO₂ < 92%; (2) imputed PaO₂/FiO₂ < 300 mmHg [(1) or (2) occurring at least

SUBMITTER: Nagrebetsky A 

PROVIDER: S-EPMC11469209 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature