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Social determinants of injection drug use-associated bacterial infections and treatment outcomes: systematic review and meta-analysis.


ABSTRACT:

Background

Individual injecting practices (e.g., intramuscular injecting, lack of skin cleaning) are known risk factors for injection drug use-associated bacterial and fungal infections; however, social contexts shape individual behaviours and health outcomes. We sought to synthesize studies assessing potential social determinants of injecting-related infections and treatment outcomes.

Methods

We searched five databases for studies published between 1 January 2000 and 18 February 18 2021 (PROSPERO CRD42021231411). We included studies of association (aetiology), assessing social determinants, substance use, and health services exposures influencing development of injecting-related infections and treatment outcomes. We pooled effect estimates via random effects meta-analyses.<

SUBMITTER: Brothers TD 

PROVIDER: S-EPMC11469356 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature