Moderate IV Fluid Resuscitation Is Associated With Decreased Sepsis Mortality.

ABSTRACT:

Objectives

Significant practice variation exists in the amount of resuscitative IV fluid given to patients with sepsis. Current research suggests equipoise between a tightly restrictive or more liberal strategy but data is lacking on a wider range of resuscitation practices. We sought to examine the relationship between a wide range of fluid resuscitation practices and sepsis mortality and then identify the primary driver of this practice variation.

Design

Retrospective analysis of the Premier Healthcare Database.

Setting

Six hundred twelve U.S. hospitals.

Patients

Patients with sepsis and septic shock admitted from the emergency department to the ICU from January 1, 2016, to December 31, 2019.

Interventions

The volume of resuscitative IV fluid administe

SUBMITTER: Corl KA 

PROVIDER: S-EPMC11469629 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature