Potassium chloride-assisted heat treatment enhances the de-glycosylation efficiency and xanthine oxidase inhibitory activity of <i>Sophora japonica</i> L. flavonoids.

ABSTRACT: Salt-assisted heat treatment is considered an effective way to enhance the bioactivities of flavonoids in Flos Sophorae Immaturus tea (FSIt). Herein, sodium chloride (NaCl)- and potassium chloride (KCl)-assisted heat treatment was employed to process FSIt, the components, xanthine oxidase (XO) inhibitory activity, and degradation or conversion kinetics of FSIt flavonoids were recorded. Results showed that KCl-assisted heat treatment significantly increased the XO inhibition rate of FSIt from 28.05 % to 69.50 %. The de-glycosylation of flavonoids was the crucial reason for enhancing XO inhibitory activity. Notably, KCl exhibited a better catalytic effect on the de-glycosylation reaction than NaCl. Meanwhile, conversion kinetics showed that the generation rate of quercetin, kaempferol

SUBMITTER: Li J 

PROVIDER: S-EPMC11470184 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature