Proportion and risk factors for hospital-acquired venous thromboembolism in children: a systematic review and meta-analysis of data from 20 million individuals in 22 countries.

ABSTRACT:

Background

Hospital-acquired venous thromboembolism (HA-VTE) in children has been widely regarded.

Objectives

We aimed to analyze the proportion and risk factors for HA-VTE in hospitalized children.

Methods

We conducted a comprehensive systematic search across 4 databases from 1990 to 2023. Cochran Q test was used to evaluate the heterogeneity of the effect sizes of study, and I² statistic was used to quantify the heterogeneity. Pooled estimates were calculated by the inverse-variance weighted method in a fixed-effect model or a random-effect model when heterogeneity was low (I² < 25%) or high (I² > 25%), respectively.

Results

In total, 105 original papers and 20,718,294 patients were included in the study, and the proportion of

SUBMITTER: Zhou J 

PROVIDER: S-EPMC11470410 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature