Global, regional, and national burden of retinoblastoma in infants and young children: findings from the global burden of disease study 1990-2021.

ABSTRACT:

Background

Retinoblastoma is considered a lethal but curable malignancy often presenting in childhood. We investigated its global, regional, and national burden among infants and young children from 1990 to 2021.

Methods

We obtained data on retinoblastoma incidence, prevalence, mortality, and disability-adjusted life years (DALYs) from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021. Trends were analysed using joinpoint regression to calculate annual percentage changes. Spearman's rank correlation and locally estimated scatterplot smoothing regression were used to assess the relationship between retinoblastoma burden and sociodemographic index.

Findings

In 2021, the global incidence, prevalence, mortality, and DALYs of retinoblastoma were 0.82 (95

SUBMITTER: Chen J 

PROVIDER: S-EPMC11470412 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature