Lifestyle score is associated with cellular immune profiles in healthy Tanzanian adults.

ABSTRACT: Immune system and vaccine responses vary across geographical locations worldwide, not only between high and low-middle income countries (LMICs), but also between rural and urban populations within the same country. Lifestyle factors such as housing conditions, exposure to microorganisms and parasites and diet are associated with rural-and urban-living. However, the relationships between these lifestyle factors and immune profiles have not been mapped in detail. Here, we profiled the immune system of 100 healthy Tanzanians living across four rural/urban areas using mass cytometry. We developed a lifestyle score based on an individual's household assets, housing condition and recent dietary history and studied the association with cellular immune profiles. Seventeen out of 80 immune cell clu

SUBMITTER: Pyuza JJ 

PROVIDER: S-EPMC11470418 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature