Multimodal apparent diffusion MRI model in noninvasive evaluation of breast cancer and Ki-67 expression.

ABSTRACT:

Background

To assess the capability of multimodal apparent diffusion (MAD) weighted magnetic resonance imaging (MRI) to distinguish between malignant and benign breast lesions, and to predict Ki-67 expression level in breast cancer.

Methods

This retrospective study was conducted with 93 patients who had postoperative pathology-confirmed breast cancer or benign breast lesions. MAD images were acquired using a 3.0 T MRI scanner with 16 b values. The MAD parameters, as flow (f_F, D_F), unimpeded (fluid) (f_UI), hindered (f_H, D_H, and α_H), and restricted (f_R, D_R), were calculated. The differences of the parameters were compared by Mann-Whitney U test between the benign/malignant lesions and high/

SUBMITTER: Chang H 

PROVIDER: S-EPMC11470582 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature