Efficacy of pharmacological interventions for ADHD: protocol for an updated systematic review and dose-response network meta-analysis.

ABSTRACT:

Background

Attention-deficit/hyperactivity disorder (ADHD) affects approximately 5% of children globally, with symptoms often persisting into adulthood. While pharmacological interventions are commonly employed for management, understanding the optimal dosing for efficacy and tolerability remains crucial. This study aims to conduct a dose-response network meta-analysis to estimate the efficacy of pharmacological treatments across different doses, aiming to inform clinical decision-making and improve treatment outcomes.

Methods

This updated systematic review will include randomized controlled trials evaluating ADHD medication efficacy in children, adolescents, and adults. An updated search from a 2018 NMA will be conducted across multiple electronic databases with no language

SUBMITTER: Nourredine M 

PROVIDER: S-EPMC11470584 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature