Bacterial and clinical metabolic signatures and their interactions in obese patients post-bariatric surgery.

ABSTRACT:

Background

Obesity is a growing health concern in China, closely linked to metabolic disorders such as type 2 diabetes. Laparoscopic Sleeve Gastrectomy (LSG) is effective in promoting weight loss and improving metabolic outcomes. Emerging evidence highlights the role of gut microbiota in metabolic regulation, yet the specific alterations in gut microbiota and their association with metabolic changes post-surgery in Chinese patients remain unclear. Understanding these shifts could provide key insights into optimizing treatment strategies for metabolic improvement following bariatric surgery.

Methods

Stool samples and clinical data were collected from 30 obese patients before and 6 months after surgery. The composition of the gut microbiota was analyzed through 16S rRNA sequen

SUBMITTER: Hu M 

PROVIDER: S-EPMC11470734 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature