Prognostic value of TMTC1 in pan-cancer analysis.

ABSTRACT:

Background

Transmembrane and tetratricopeptide repeat containing 1 (TMTC1) is a recently discovered enzyme involved in the O-mannosylation of cadherins and protocadherins. It has been implicated in various types of cancer, but the overall prognostic significance of TMTC1 in pan-cancer and its potential as an immunotherapeutic target remain unclear.

Methods

We applied various bioinformatics methods to investigate the potential oncogenic roles of TMTC1 using public databases. This analysis involved examining the expression, prognosis, genetic alterations, immune infiltration, immunotherapy response, drug sensitivity, and regulatory mechanisms of the TMTC1 gene in diverse cancer types.

Results

In this study, we observed that TMTC1 expre

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11471174 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature