Untangling lineage introductions, persistence and transmission drivers of HP-PRRSV sublineage 8.7.

ABSTRACT: Despite a rapid expansion of Porcine reproductive and respiratory syndrome virus (PRRSV) sublineage 8.7 over recent years, very little is known about the patterns of virus evolution, dispersal, and the factors influencing this dispersal. Relying on a national PRRSV surveillance project established over 20 years ago, we expand the available genomic data of sublineage 8.7 from China. We perform independent interlineage and intralineage recombination analyses for the entire study period, which showed a heterogeneous recombination pattern. A series of Bayesian phylogeographic analyses uncover the role of Guangdong as an important infection hub within Asia. The spatial spread of PRRSV is highly linked with a composite of human activities and the heterogeneous provincial distribution of the swin

SUBMITTER: Sun Y 

PROVIDER: S-EPMC11471759 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature