Exploring the Association Between Systemic Lupus Erythematosus and High-Density Lipoproteins: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

Systemic lupus erythematosus (SLE) is an autoimmune disease with inflammation as a critical feature. Recently, high-density lipoprotein cholesterol (HDLc) have been evidenced to have anti-inflammatory effects, suggesting a potential link between HDL and SLE that needs to be thoroughly studied. The aim was to explore the association between SLE and HDLc through a systematic review with meta-analysis.

Methods

A systematic review with meta-analysis was conducted to assess mean differences in HDL levels between patients with SLE and healthy controls. Both qualitative and quantitative syntheses were performed, including an assessment of heterogeneity using I², a publication bias evaluation, a methodologic quality assessment, and a forest plot under a random e

SUBMITTER: Perez-Ocampo J 

PROVIDER: S-EPMC11471950 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature