Chronic Cannabis users exhibit altered oscillatory dynamics and functional connectivity serving visuospatial processing.

ABSTRACT:

Background

Cannabis is the most widely used psychoactive drug in the United States. While multiple studies have associated acute cannabis consumption with alterations in cognitive function (e.g., visual and spatial attention), far less is known regarding the effects of chronic consumption on the neural dynamics supporting these cognitive functions.

Methods

We used magnetoencephalography (MEG) and an established visuospatial processing task to elicit multi-spectral neuronal responses in 44 regular cannabis users and 53 demographically matched non-user controls. To examine the effects of chronic cannabis use on the oscillatory dynamics underlying visuospatial processing, neural responses were imaged using a time-frequency resolved beamformer and compared across groups.

Resu

SUBMITTER: Castelblanco CA 

PROVIDER: S-EPMC11471968 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature