Bronchial washing fluid sequencing is useful in the diagnosis of lung cancer with necrotic tumor.

ABSTRACT:

Background

Early-stage lung cancers detected by low-dose computed tomography (CT) often require confirmation through invasive procedures due to the absence of endobronchial lesions. This study assesses the diagnostic utility of bronchial washing fluid (BW) sequencing, a less invasive alternative, aiming to identify patient characteristics most suited for this approach.

Methods

From June 2017 to March 2018, we conducted a prospective cohort study by enrolling patients with incidental lung lesions suspected of early-stage lung cancer at two independent hospitals, and 114 were diagnosed with lung cancer while 50 were diagnosed with benign lesions. BW sequencing was performed using a targeted gene panel, and the clinical characteristics of patients detected with cancer through s

SUBMITTER: Lim JH 

PROVIDER: S-EPMC11472095 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature