Accuracy of coronary computed tomography angiography-derived quantitative flow ratio for onsite assessment of coronary lesions.

ABSTRACT:

Background

Coronary computed tomography angiography (CCTA)-derived Murray law-based quantitative flow ratio (CT-μFR) is a novel non-invasive method for fast computation of fractional flow reserve (FFR) from CCTA images, yet its diagnostic performance remains to be prospectively validated.

Aims

We aimed to evaluate the diagnostic performance of onsite CT-μFR in patients with coronary artery disease.

Methods

This prospective, single-centre trial enrolled patients with ≥1 lesion with 30-90% diameter stenosis on CCTA and planned invasive coronary angiography (ICA) within 30 days. CT-μFR, ICA-derived μFR and FFR were evaluated separately in a blinded fashion. The primary endpoint was the diagnostic accuracy of CT-μFR in identifying patients with haemodynamically significan

SUBMITTER: Weng T 

PROVIDER: S-EPMC11472136 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature