Cognitive impairments in autoimmune encephalitis: the role of autoimmune antibodies and oligoclonal bands.

ABSTRACT:

Introduction

The presence of oligoclonal bands (OCBs) in cerebrospinal fluid (CSF) is a pivotal diagnostic marker for multiple sclerosis (MS). These bands play a crucial role in the diagnosis and understanding of a wide array of immune diseases. In this study, we explore the relationship between the cognitive profile of autoimmune encephalitis (AIE) and the presence of OCBs in CSF, with a particular emphasis on NMDA receptor antibodies.

Methods

We studied a cohort of 21 patients across five tertiary centers, segregated into two distinct categories. One group comprised individuals who tested positive only for autoimmune encephalitis antibodies indicative of encephalitis, while the other group included patients whose CSF was positive for both autoimmune encephalitis antibodies

SUBMITTER: Rozenberg A 

PROVIDER: S-EPMC11472350 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature