Optimizing outcomes in drug-resistant mesial temporal lobe epilepsy patients undergoing stereoelectroencephalography-guided radiofrequency thermocoagulation.

ABSTRACT:

Background

Mesial temporal lobe epilepsy (MTLE) epileptiform discharges have been reported to arise from the hippocampus or the extrahippocampal medial temporal cortex, such as the amygdala, and then propagate to the temporal lobe cortex. The surgical ablation of which of these structures would result in a better postoperative outcome is debatable.

Objective

To assess the possible factors that might have influenced the postoperative outcome of a group of drug-resistant mesial MTLE patients who underwent stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RFTC).

Design

Single-center, retrospective.

Methods

The present study utilized a pre- and postoperative gray matter voxel-by-voxel ablation mapping comparison approach, along with a whi

SUBMITTER: Jean S 

PROVIDER: S-EPMC11472416 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature