Left atrial to ventricular volume ratio and relation to fitness, cardiovascular risk factors, and diastolic function in healthy individuals: the HUNT Study.

ABSTRACT:

Aims

Left atrial (LA) and ventricular (LV) remodelling is thought to be balanced in healthy individuals, and the LA end-systolic volume (LAV) to LV end-diastolic volume (LVEDV) ratio (LA:LV) could help discriminate between pathological and physiological LA enlargement. We aimed to assess LA:LV and its associations with age, sex, and cardiovascular risk factors HbA1C, body mass index (BMI), systolic blood pressure, and peak oxygen uptake (VO_2peak). The association to measures of LV diastolic function and filling pressures were compared with LAV and LA reservoir strain.

Methods and results

Cardiopulmonary exercise testing and measurement of risk factors 10 years apart and echocardiography at follow-up was performed in 1348 healthy adults [52% women, mean (SD) age 59

SUBMITTER: Sabo S 

PROVIDER: S-EPMC11472746 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature