Interaction between non-alcoholic fatty liver disease and obesity on the risk of developing cardiovascular diseases.

ABSTRACT:

Backgrounds

This investigation seeks to explore the correlation between nonalcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVDs), and to to provide evidence for the prevention and treatment of CVDs.

Methods

This study utilized data from the Jinchang cohort platform, including 19,399 participants without pre-existing major CVDs. Based on the general population and gender stratification, Cox models were used to analyze the risk of NAFLD for CVDs. The combined effect of NAFLD and different obesity indicators on CVDs was analyzed by additive and multiplicative interaction models and subgroups.

Results

There were 3129 NAFLD patients out of 19399 subjects, and 723 (23.11%) of them had the CVD. After adjusting for multiple confounding factors, the Cox mode

SUBMITTER: Wang X 

PROVIDER: S-EPMC11473819 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature