Network connectivity underlying information processing speed in children: Application of a pediatric brain tumor survivor injury model.

ABSTRACT: Elucidating how adaptive and maladaptive changes to the structural connectivity of brain networks influences neural synchrony, and how this structure-function coupling impacts cognition is an important question in human neuroscience. This study assesses these links in the default mode and executive control networks during resting state, a visual-motor task, and through computational modeling in the developing brain and in acquired brain injuries. Pediatric brain tumor survivors were used as an injury model as they are known to exhibit cognitive deficits, structural connectivity compromise, and perturbations in neural communication. Focusing on information processing speed to assess cognitive performance, we demonstrate that during the presence and absence of specific task demands, structur

SUBMITTER: Al Dahhan NZ 

PROVIDER: S-EPMC11474185 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature