MASLD-related HCC: Multicenter study comparing patients with and without cirrhosis.

ABSTRACT:

Background & aims

Despite its growing incidence, hepatocellular carcinoma (HCC) related to metabolic dysfunction-associated steatotic liver disease (MASLD) in non-cirrhotic livers remains poorly characterized. We compared the characteristics, management, survival, and trends of MASLD-related HCC in patients with or without underlying cirrhosis in a large multicenter cohort.

Methods

A total of 354 cases of MASLD-related HCC presented at the liver tumor meetings of four French university hospitals between 2007 and 2018 were included in the study. Data were extracted from the meetings' databases and from the French Birth and Death Registry.

Results

Of HCC cases, 35% occurred in the absence of cirrhosis. HCC was diagnosed through screening in 60% of patients with cirrhosi

SUBMITTER: Vitellius C 

PROVIDER: S-EPMC11474187 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature