L-shaped association of thiamine intake and risk for peripheral artery disease in US adults: a cross-sectional study.

ABSTRACT:

Background

The relationship between thiamine intake and risk for peripheral artery disease (PAD) is unknown. We aimed to clarify the role of thiamine intake on risk for PAD and the implications of this relationship. The secondary objective of this study is to explore the potential non-linear dose-response relationship between exposure to thiamine intake and outcome risk for PAD.

Methods

We conducted a cross-sectional study involving 6,112 participants with US adults from the National Health and Nutrition Examination Survey (1999-2004). Logistic regression and restricted cubic spline were utilized to substantiate the research objectives.

Results

The overall prevalence of risk for PAD was 7.9, 51% in males and 49% in females. After multivariable adjustment, lower thiami

SUBMITTER: Dong Z 

PROVIDER: S-EPMC11474247 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature