Depressive symptomatology, NT-proBNP levels and health status in patients with heart failure: a prospective observational study.

ABSTRACT:

Background

Depressive symptoms frequently occur in patients with heart failure (HF). However, research on the relationship between these symptoms and N-terminal pro-brain natriuretic peptide (NT-proBNP), a key biomarker for HF severity and treatment, is scarce and yields inconsistent results.

Aims

This study investigates the relationship among depressive symptomatology, NT-proBNP and health status in a cohort of patients with HF. Additionally, it assesses the impact of depressive symptoms on their clinical outcomes.

Methods

A cohort of 151 patients with HF was followed for 1 year. The Hospital Anxiety and Depression Scale-Depression (HADS-D) Score was used to assess anxiety and depressive symptoms, and NT-proBNP levels were measured. Health status was evaluated using

SUBMITTER: Balata M 

PROVIDER: S-EPMC11474672 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature