Unraveling the brain dynamics of Depersonalization-Derealization Disorder: a dynamic functional network connectivity analysis.

ABSTRACT:

Background

Depersonalization-Derealization Disorder (DPD), a prevalent psychiatric disorder, fundamentally disrupts self-consciousness and could significantly impact the quality of life of those affected. While existing research has provided foundational insights for this disorder, the limited exploration of brain dynamics in DPD hinders a deeper understanding of its mechanisms. It restricts the advancement of diagnosis and treatment strategies. To address this, our study aimed to explore the brain dynamics of DPD.

Methods

In our study, we recruited 84 right-handed DPD patients and 67 healthy controls (HCs), assessing them using the Cambridge Depersonalization Scale and a subliminal self-face recognition task. We also conducted a Transcranial Direct Current Stimulation (tDCS

SUBMITTER: Zheng S 

PROVIDER: S-EPMC11475637 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature