A Proteomic Analysis of Nasopharyngeal Carcinoma in a Moroccan Subpopulation.

ABSTRACT:

Background

Nasopharyngeal carcinoma (NPC) is a distinct cancer of the head and neck that is highly prevalent in Southeast Asia and North Africa. Though an extensive analysis of environmental and genetic contributors has been performed, very little is known about the proteome of this disease. A proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissues can provide valuable information on protein expression and molecular patterns for both increasing our understanding of the disease and for biomarker discovery. To date, very few NPC proteomic studies have been performed, and none focused on patients from Morocco and North Africa.

Methods

Label-free Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) was used to perform a proteomic analysis of FFPE tissue sample

SUBMITTER: Reffai A 

PROVIDER: S-EPMC11476039 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature