Characterisation of Three Ovine KRTAP13 Family Genes and Their Association with Wool Traits in Chinese Tan Sheep.

ABSTRACT: Understanding the genetic basis of wool traits is crucial for improving wool production. In this study, we investigated the ovine KAP13 gene family, which in humans contains multiple members, while only one member has been identified to date in sheep. Three ovine KRTAP13 genes, likely representing KRTAP13-1, KRTAP13-2, and KRTAP13-4, were identified through sequence analysis and phylogenetic comparisons. These genes are positioned on chromosome 1, between KRTAP15-1 and KRTAP27-1, in a pattern that is like the arrangement in humans but not identical. Analyses revealed multiple sequence variants of each gene in 356 sheep from a variety of wool, meat, and dual-purpose breeds. The effect of these genes on four fibre traits: mean fibre curvature (MFC),

SUBMITTER: Bai L 

PROVIDER: S-EPMC11476196 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature