Efficient Production of 4'-Hydroxydihydrochalcones Using Non-Conventional Yeast Strains.

ABSTRACT: The quest for novel therapeutic agents has rekindled interest in natural products, particularly those derived from biotransformation processes. Dihydrochalcones, a class of plant secondary metabolites, exhibit a range of pharmacological properties. Chalcone and dihydrochalcone compounds with the characteristic 4'-hydroxy substitution are present in 'dragon's blood' resin, known for its traditional medicinal uses and complex composition, making the isolation of these compounds challenging. This study investigates the efficient production of 4'-hydroxydihydrochalcones using non-conventional yeast strains. We evaluated the biotransformation efficiency of various 4'-hydroxychalcone substrates utilizing yeast strains such as Yarrowia lipolytica KCh 71, Saccharomyces cerevisiae KCh

SUBMITTER: Chlipala P 

PROVIDER: S-EPMC11476679 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature