Insights of Expression Profile of Chemokine Family in Inflammatory Bowel Diseases and Carcinogenesis.

ABSTRACT: Chemokines are integral components of the immune system and deeply involved in the pathogenesis and progression of inflammatory bowel disease (IBD) and colorectal cancer (CRC). Although a considerable amount of transcriptome data has been accumulated on these diseases, most of them are limited to a specific stage of the disease. The purpose of this study is to visually demonstrate the dynamic changes in chemokines across various stages of bowel diseases by integrating relevant datasets. Integrating the existing datasets for IBD and CRC, we compare the expression changes of chemokines across different pathological stages. This study collected 11 clinical databases from various medical centers around the world. Patients: Data of patient tissue types were classified into IBD, colorectal adeno

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11476924 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature