Codon Bias of the <i>DDR1</i> Gene and Transcription Factor EHF in Multiple Species.

ABSTRACT: Milk production is an essential economic trait in cattle, and understanding the genetic regulation of this trait can enhance breeding strategies. The discoidin domain receptor 1 (DDR1) gene has been identified as a key candidate gene that influences milk production, and ETS homologous factor (EHF) is recognized as a critical transcription factor that regulates DDR1 expression. Codon usage bias, which affects gene expression and protein function, has not been fully explored in cattle. This study aims to examine the codon usage bias of DDR1 and EHF transcription factors to understand their roles in dairy production traits. Data from 24 species revealed that both DDR1 and EHF predominantly used G/C-ending codons, with the GC3 content averaging 75.49% for DDR1

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11477322 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature