Contribution of the Mobilome to the Configuration of the Resistome of Corynebacterium striatum.

ABSTRACT: Corynebacterium striatum, present in the microbiota of human skin and nasal mucosa, has recently emerged as a causative agent of hospital-acquired infections, notable for its resistance to multiple antimicrobials. Its mobilome comprises several mobile genetic elements, such as plasmids, transposons, insertion sequences and integrons, which contribute to the acquisition of antimicrobial resistance genes. This study analyzes the contribution of the C. striatum mobilome in the transfer and dissemination of resistance genes. In addition, integrative and conjugative elements (ICEs), essential in the dissemination of resistance genes between bacterial populations, whose role in C. striatum has not yet been studied, are examined. This study examined 365 C. striatum gen

SUBMITTER: Urrutia C 

PROVIDER: S-EPMC11477358 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature